Perspectives in aldosterone and renin control.

摘要: Summary: The factors which control sodium excretion by the kidney - glomerular filtration rate, action of steroid hormones to increase tubular reabsorption sodium, and other influences on reabsorption, often grouped together under general heading “third factor”, e.g. proximal salt losing hormone, oncotic pressure vascular redistribution within have been reviewed Earley Daugharty in 19691and Ehrlick 19682. Aldosterone is major mineralocorticoid adrenal gland as such has an obvious ranking amongst those variables can influence metabolism. another important relation with through pressor peptide hormone angiotensin II one three known be able directly stimulate zona glo-merulosa cortex secrete aldosterone. Renin a proteolytic enzyme released from renal acts upon specific globulin plasma (renin substrate orangiotensino-gen) produce decapeptide I. This turn converted into cleavage dipeptide C-terminal end. conversion accomplished “converting enzymes” occur blood or lungs. Angiotensin believed some most variable producing increased aldosterone secretion, especially during restriction. Because this case, determine level could more than renin secretion per se, only sector complex system operating arterial concentration.