Perfil de resistencia a los antimicrobianos en agentes causantes de infección del tracto urinario en niños chilenos: Programa de vigilancia PRONARES

摘要: Background: PRONARES (Programa Nacional de Vigilancia Resistencia) is a national surveillance program for antimicrobial susceptibility, focused in different syndromes and among these, urinary tract infections. The work done laboratory net that uses common protocols whose data are centrally analyzed using the WHONET program. Aim: To analyze pattern of susceptibility agents causing infections children period 1997-1999. Material methods: In study period, 5,525 strains were analyzed. Of 2,307 came from pediatric patients (1,495 hospitalized 803 ambulatory). Results: most causative agent was E. coli 74,2% cases, followed by Klebsiella spp 8,2% other lower frequency. strains, 74% resistant to ampicillin, 52% clotrimoxazole 30% first generation cephalosporins. These sensitive second third cephalosporins, aminoglycosides, ciprofloxacin nitrofurantoin. Strains nosocomial or community had similar susceptibility. high rate resistance (over 40%), even higher strains. It 90% susceptible 100% imipenem. All centers which with exception center significantly levels. Conclusions: current therapeutic recommendations caused E coli, still pertinent, but use cephalosporins must be cautious. treatment requires an individual antibiogram (Rev Med Chile 2001; 129: 877-885).