Prognostic Value of Nuclear β-catenin Overexpression at Invasive Front in Colorectal Cancer for Synchronous Liver Metastasis

作者: Lin Wang , Hongxia Cheng , Ying Liu , Lei Wang , Wenbin Yu

DOI: 10.1245/S10434-010-1519-9

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摘要: Background β-catenin plays an important role in colorectal tumorigenesis. Relatively little is known about the relationship between β-catenin overexpression and liver metastasis. The purpose of this study was to investigate whether nuclear cancer associated with synchronous

参考文章(38)
Thomas Brabletz, Andreas Jung, Simone Spaderna, Falk Hlubek, Thomas Kirchner, Migrating cancer stem cells — an integrated concept of malignant tumour progression Nature Reviews Cancer. ,vol. 5, pp. 744- 749 ,(2005) , 10.1038/NRC1694
S. T. Pals, V. J. M. Wielenga, G. R. Adolf, F. M. Van Den Berg, K.-H. Heider, P. Herrlich, H. Ponta, G. J. A. Offerhaus, Expression of CD44 Variant Proteins in Human Colorectal Cancer Is Related to Tumor Progression Cancer Research. ,vol. 53, pp. 4754- 4756 ,(1993)
Keiichi Iwaya, Kosuke Oikawa, Seitaro Semba, Benio Tsuchiya, Yasuo Mukai, Toshiya Otsubo, Toshitaka Nagao, Miki Izumi, Masahiko Kuroda, Hideharu Domoto, Kiyoshi Mukai, Correlation between liver metastasis of the colocalization of actin-related protein 2 and 3 complex and WAVE2 in colorectal carcinoma Cancer Science. ,vol. 98, pp. 992- 999 ,(2007) , 10.1111/J.1349-7006.2007.00488.X
Atsushi Nanashima, Hiroyuki Yamaguchi, Terumitsu Sawai, Toru Yasutake, Takashi Tsuji, Masaaki Jibiki, Eiichiro Yamaguchi, Tohru Nakagoe, Hiroyoshi Ayabe, Expression of adhesion molecules in hepatic metastases of colorectal carcinoma: Relationship to primary tumours and prognosis after hepatic resection Journal of Gastroenterology and Hepatology. ,vol. 14, pp. 1004- 1009 ,(1999) , 10.1046/J.1440-1746.1999.01991.X
Yosuke Adachi, Masafumi Inomata, Kenji Kakisako, Koichi Sato, Norio Shiraishi, Seigo Kitano, Histopathologic characteristics of colorectal cancer with liver metastasis. Diseases of The Colon & Rectum. ,vol. 42, pp. 1053- 1056 ,(1999) , 10.1007/BF02236702
Riccardo Fodde, Thomas Brabletz, Wnt/β-catenin signaling in cancer stemness and malignant behavior Current Opinion in Cell Biology. ,vol. 19, pp. 150- 158 ,(2007) , 10.1016/J.CEB.2007.02.007
Shin Fujita, Hirokazu Taniguchi, Takashi Yao, Tadakazu Shimoda, Hideki Ueno, Takashi Hirai, Masayuki Ohue, Multi-institutional study of risk factors of liver metastasis from colorectal cancer: correlation with CD10 expression International Journal of Colorectal Disease. ,vol. 25, pp. 681- 686 ,(2010) , 10.1007/S00384-010-0913-X
Ian C. Talbot, Sheila Ritchie, Monica H. Leighton, Anthony O. Hughes, H. J. R. Bussey, Basil C. Morson, The clinical significance of invasion of veins by rectal cancer. British Journal of Surgery. ,vol. 67, pp. 439- 442 ,(2005) , 10.1002/BJS.1800670619
Obul R Bandapalli, Susanne Dihlmann, Reham Helwa, Stephan Macher‐Goeppinger, Jurgen Weitz, Peter Schirmacher, Karsten Brand, Transcriptional activation of the β-catenin gene at the invasion front of colorectal liver metastases† The Journal of Pathology. ,vol. 218, pp. 370- 379 ,(2009) , 10.1002/PATH.2539