Preparation and evaluation of rigid porous polyacrylamide‐based strong cation‐exchange monolithic columns for capillary electrochromatography
作者： Jing Dong , Junjie Ou , Xiaoli Dong , Renan Wu , Mingliang Ye
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摘要: A CEC monolithic column with strong cation-exchange (SCX) stationary phase based on hydrophilic monomers was prepared by in situ polymerization of acrylamide, methylenebisacrylamide, and 2-acrylamido-2-methyl-1-propanesulfonic acid (AMPS) a complete organic binary porogenic solvent consisting DMSO dodecanol. The sulfonic groups provided the monomer AMPS surface generate an EOF from anode to cathode, serve as SCX at same time. exhibited normal-phase chromatographic behavior for neutral analytes. For charged analytes, electrostatic interaction/repulsion monolith observed. has been successfully employed electrochromatographic separation basic drugs, peptides, alkaloids extracted natural products.
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