Ecotoxicology of polychlorinated biphenyls in fish—a critical review
作者： T. B. Henry
DOI: 10.3109/10408444.2015.1038498
关键词:
摘要: Polychlorinated biphenyls (PCBs) are widespread persistent anthropogenic contaminants that can accumulate in tissues of fish. The toxicity PCBs and their transformation products has been investigated for nearly 50 years, but there is a lack consensus regarding the effects these environmental on wild fish populations. objective this review to critically examine investigations evaluate publicly available databases evidence Biological activity limited small proportion PCB congeners [e.g., dioxin-like (DL-PCBs)] occurs at concentrations typically orders magnitude higher than levels detected Induction biomarkers consistent with exposure (e.g., induction cytochrome P450 monooxygenase system) evaluated frequently shown be induced from some environments, does not appear reports damage (i.e., effect) biomolecules oxidative injury) Numerous endocrine system dysfunction or other organ systems have conducted fish, collectively no Early life stage DL-PCBs occur reported embryos, results do support an association between decreased survival early stages Overall, appears little had any effect health
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