Use of remifentanil to reduce propofol injection pain and the required propofol dose in upper digestive tract endoscopy diagnostic tests

摘要: BACKGROUND AND OBJECTIVES: The introduction of propofol (2,6-diisopropylphenol) as a sedative agent has transformed the area sedation for endoscopic procedures. However, major drawback with use is its high incidence injection pain. most widely used technique in reducing pain through association other drugs. aim this study was to evaluate effect remifentanil-propofol combination on and influence total dose required upper digestive tract endoscopy (UDE) diagnostic tests. METHOD: One hundred five patients undergoing were evaluated randomly divided into 3 groups 35 each. Control Group received alone; Study-group 1 remifentanil at fixed 0.2 mg/kg combined propofol; 2 0.3 propofol. test evaluated. sample very similar regarding age, weight, height, sex, physical status. Statistical analysis performed according nature data. Student'st-test compare mean height (cm), (mg/kg) variables between groups. χ2 status, significance level < 0.05. RESULTS: There significant statistical difference control group parameters used. there no differences two these parameters. CONCLUSION: We conclude that doses effective both