The Essential Role of Hippocampal CA1 NMDA Receptor–Dependent Synaptic Plasticity in Spatial Memory

作者: Joe Z Tsien , Patricio T Huerta , Susumu Tonegawa

DOI: 10.1016/S0092-8674(00)81827-9

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摘要: … impaired LTP in the CA1 region of the hippocampus and a deficit in spatial learning (49, 50). … are consistent with the notion that hippocampal LTP is the synaptic mechanism for spatial …

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