作者: Dirk Brenner , Heiko Blaser , Tak W. Mak
DOI: 10.1038/NRI3834
关键词:
摘要: In this Review, the authors describe how tumour necrosis factor (TNF) signals via its receptors. They explain TNF is able to promote cell survival or death in different contexts and discuss consequences of deregulated receptor signalling for chronic human diseases. Finally, they new strategies targeting clinic.