Detection of fungal organisms in saliva from HIV-infected children: a preliminary cytologic analysis
作者： Cron Sg , Shearer Wt , Demmler Gj , Kline Mw , Rossmann Sn
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摘要: Purpose: Fungal infections in HIV-infected individuals are associated with advancement of disease. In pediatric HIV infection, symptomatic children have a significantly higher incidence clinical candidiasis and persistent drug-resistant than do asymptomatic chiMren. The purpose this preliminary cytologic study was to determine the prevalence offungal organisms whole unstimulated saliva j~om vertically acquired H1V infection. Methods: subjects included 27 l HIV-exposed, but uninfected, Whole obtained for evaluation (hematoxylin eosin, silver stains) selected samples evaluated by electron microscopy. Results: Yeast hyphae were identified cytologically 19% (22% I-IIV-infected, 11% HIV-infected) and9% children. found more j~equently moderate (18%) severe (27%) suppression. Fungi fkequent antiretroviral therapy (22%) vs no (0%) antifungal (20%) vs. (7%). hyphal fungal forms prevalent HEft-infection suppression, those receiving agents, medications. Conclusion: may reflect oral carriage or mucosal colonization, which influence development clinically significant these immunocompromised (Pediatr Dent 20:162-68, 1998)
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