Prevalence of oral soft tissue lesions in HIV-infected minority children treated with highly active antiretroviral therapies.
作者： Flanagan Ma , Fine D , Houpt M , Koenigsberg , Barasch A
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摘要: Purpose: This project studied the prevalence of oral soft tissue disease in HIV-infected children treated with highly active antiretroviral therapy (HAART). Methods: Thirty-eight participated study. Twenty-three these patients were HAART while 14 received exclusively reverse transcriptase inhibitors (RTI) and served as controls. The examined three times at approximately one-month intervals their health history laboratory data abstracted from medical charts. Analyses performed to determine differences lesion between treatment groups well no regard immune differences. Results: Thirty (79%) had lesions detected least one visit. There specific compared RTI-treated children. However, a trend for more candidiasis latter group was observed. Subjects lower CD4 counts (P=0.04) percentages (P=0.01) but similar viral loads when without disease. Conclusions: does not appear significantly affect Presence associated decreased immunity may signal advancing disease.(Pediatr Dent 22:287-291, 2000)
参考文章(19)
L Ketchem, R J Berkowitz, T Rakusan, L McIlveen, D Forrester, Oral findings in HIV-seropositive children. Pediatric Dentistry. ,vol. 12, pp. 143- 146 ,(1990)
Canchola Aj, Ramos-Gomez Fj, Hilton Jf, Greenspan Js, Greenspan D, Maldonado Ya, Risk factors for HIV-related orofacial soft-tissue manifestations in children Pediatric Dentistry. ,vol. 18, pp. 121- ,(1996)
Cron Sg, Shearer Wt, Demmler Gj, Kline Mw, Rossmann Sn, Simon Cl, Flaitz Cm, Carter Ab, Hicks Mj, Detection of fungal organisms in saliva from HIV-infected children: a preliminary cytologic analysis Pediatric Dentistry. ,vol. 20, pp. 162- 168 ,(1998)
Mitchell H. Katz, Prognostic Significance of Oral Lesions in Children With Perinatally Acquired Human Immunodeficiency Virus Infection Archives of Pediatrics & Adolescent Medicine. ,vol. 147, pp. 45- 48 ,(1993) , 10.1001/ARCHPEDI.1993.02160250047015
José M. Aguirre, Maria A. Echebarria, Esther Ocina, Laureano Ribacoba, Miguel Montejo, Reduction of HIV-associated oral lesions after highly active antiretroviral therapy. Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology. ,vol. 88, pp. 114- 115 ,(1999) , 10.1016/S1079-2104(99)70124-1
D. Moniaci, D. Greco, G. Flecchia, R. Raiteri, A. Sinicco, Epidemiology, clinical features and prognostic value of HIV-1 related oral lesions. Journal of Oral Pathology & Medicine. ,vol. 19, pp. 477- 481 ,(1990) , 10.1111/J.1600-0714.1990.TB00790.X
Penelope J. Leggott, Oral manifestations of HIV infection in children Oral Surgery, Oral Medicine, Oral Pathology. ,vol. 73, pp. 187- 192 ,(1992) , 10.1016/0030-4220(92)90193-T
ANN J. MELVIN, KATHLEEN M. MOHAN, LAURA A. MANNS ARCUINO, REVA E. EDELSTEIN, LISA M. FRENKEL, Clinical, virologic and immunologic responses of children with advanced human immunodeficiency virus type 1 disease treated with protease inhibitors. Pediatric Infectious Disease Journal. ,vol. 16, pp. 968- 974 ,(1997) , 10.1097/00006454-199710000-00013
D. Moniaci, M. Cavallari, D. Greco, M. Bruatto, R. Raiteri, E. Palomba, P. A. Tovo, A. Sinicco, Oral lesions in children born to HIV–1 positive women Journal of Oral Pathology & Medicine. ,vol. 22, pp. 8- 11 ,(1993) , 10.1111/J.1600-0714.1993.TB00111.X
MD Begg, IB Lamster, KS Panageas, D. Mitchell-Lewis, JA Phelan, JT Grbic, A prospective study of oral lesions and their predictive value for progression of HIV disease Oral Diseases. ,vol. 3, pp. 176- 183 ,(2008) , 10.1111/J.1601-0825.1997.TB00032.X