The bacterial pan-genome: a new paradigm in microbiology
作者： Giuseppe D’Auria , Francisco Rodríguez-Valera , Alex Mira , Ana B. Martín-Cuadrado
关键词:
摘要: Bacterial strains belonging to the same species vary considerably in gene content. Thus, genetic repertoire of a given (its “pan-genome”) is much larger than content individual strains. These variations DNA material, together with differences genomic structure and nucleotide polymorphisms among strains, confer upon prokaryotic phenomenal adaptability. Although approach sequencing multiple from single remains main often easiest way study pan-genome, feasible alternatives include those related hybridization. In other cases, use metagenomic sequences already applicable by data mining growing databases. Eventually, single-cell genome might be ideal solution. The pan-genome concept has important consequences for we understand bacterial evolution, adaptation, population structure, as well more applied issues such vaccine design or identification virulence genes. [Int Microbiol 2010; 13(2):45-57]
unirioja.es
researchgate.net 
sci-hub.st 参考文章(69)
Lee Ca, Pathogenicity islands and the evolution of bacterial pathogens. Infectious agents and disease. ,vol. 5, pp. 1- 7 ,(1996)
Henk Bolhuis, Peter Palm, Andy Wende, Michaela Falb, Markus Rampp, Francisco Rodriguez-Valera, Friedhelm Pfeiffer, Dieter Oesterhelt, The genome of the square archaeon Haloquadratum walsbyi : life at the limits of water activity BMC Genomics. ,vol. 7, pp. 169- 169 ,(2006) , 10.1186/1471-2164-7-169
Ivy Ng, Shu-Lin Liu, Kenneth E. Sanderson, Role of Genomic Rearrangements in Producing New Ribotypes of Salmonella typhi Journal of Bacteriology. ,vol. 181, pp. 3536- 3541 ,(1999) , 10.1128/JB.181.11.3536-3541.1999
Boris A Legault, Arantxa Lopez-Lopez, Jose Carlos Alba-Casado, W Ford Doolittle, Henk Bolhuis, Francisco Rodriguez-Valera, R Thane Papke, Environmental genomics of "Haloquadratum walsbyi" in a saltern crystallizer indicates a large pool of accessory genes in an otherwise coherent species. BMC Genomics. ,vol. 7, pp. 171- 171 ,(2006) , 10.1186/1471-2164-7-171
Robert A Edwards, Beltran Rodriguez-Brito, Linda Wegley, Matthew Haynes, Mya Breitbart, Dean M Peterson, Martin O Saar, Scott Alexander, E Calvin Alexander, Forest Rohwer, Using pyrosequencing to shed light on deep mine microbial ecology. BMC Genomics. ,vol. 7, pp. 57- 57 ,(2006) , 10.1186/1471-2164-7-57
Timothy D. Read, Scott N. Peterson, Nicolas Tourasse, Les W. Baillie, Ian T. Paulsen, Karen E. Nelson, Hervé Tettelin, Derrick E. Fouts, Jonathan A. Eisen, Steven R. Gill, Erik K. Holtzapple, Ole Andreas Økstad, Erlendur Helgason, Jennifer Rilstone, Martin Wu, James F. Kolonay, Maureen J. Beanan, Robert J. Dodson, Lauren M. Brinkac, Michelle Gwinn, Robert T. DeBoy, Ramana Madpu, Sean C. Daugherty, A. Scott Durkin, Daniel H. Haft, William C. Nelson, Jeremy D. Peterson, Mihai Pop, Hoda M. Khouri, Diana Radune, Jonathan L. Benton, Yasmin Mahamoud, Lingxia Jiang, Ioana R. Hance, Janice F. Weidman, Kristi J. Berry, Roger D. Plaut, Alex M. Wolf, Kisha L. Watkins, William C. Nierman, Alyson Hazen, Robin Cline, Caroline Redmond, Joanne E. Thwaite, Owen White, Steven L. Salzberg, Brendan Thomason, Arthur M. Friedlander, Theresa M. Koehler, Philip C. Hanna, Anne-Brit Kolstø, Claire M. Fraser, The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria Nature. ,vol. 423, pp. 81- 86 ,(2003) , 10.1038/NATURE01586
Daniel A. Dalevi, Niklas Eriksen, Kimmo Eriksson, Siv G.E. Andersson, Measuring genome divergence in bacteria: a case study using chlamydian data. Journal of Molecular Evolution. ,vol. 55, pp. 24- 36 ,(2002) , 10.1007/S00239-001-0087-9
J. C. Waterhouse, D. C. Swan, R. R. B. Russell, Comparative genome hybridization of Streptococcus mutans strains. Oral Microbiology and Immunology. ,vol. 22, pp. 103- 110 ,(2007) , 10.1111/J.1399-302X.2007.00330.X
Maureen L Coleman, Matthew B Sullivan, Adam C Martiny, Claudia Steglich, Kerrie Barry, Edward F DeLong, Sallie W Chisholm, None, Genomic islands and the ecology and evolution of Prochlorococcus Science. ,vol. 311, pp. 1768- 1770 ,(2006) , 10.1126/SCIENCE.1122050
Francisco Rodriguez-Valera, Ana-Belen Martin-Cuadrado, Beltran Rodriguez-Brito, Lejla Pašić, T. Frede Thingstad, Forest Rohwer, Alex Mira, Explaining microbial population genomics through phage predation Nature Reviews Microbiology. ,vol. 7, pp. 828- 836 ,(2009) , 10.1038/NRMICRO2235