A comparative study of the duration and efficacy of tetracaine 1% and bupivacaine 0.75% in controlling pain following photorefractive keratectomy (PRK).

摘要: Objective To evaluate if topical bupivacaine 0.75% provides better pain control after excimer laser over tetracaine 1% without affecting corneal wound healing, refractive outcome of visual function. Design A prospective, double-masked trial was conducted in which 38 patients were randomized to receive either or every 30 minutes for 24 hours post-operatively. Pain recorded a four day period using Visual Analogue Scale. The rate epithelial healing assessed during digitized retro-illumination photography. performance best corrected Snellen acuity, objective measurements haze, halo and glare six month period. Results Tetracaine afforded (p = 0.05). Full closure occurred all within 72 no statistically significant difference any the parameters measured. Conclusions Contrary our expectation, longer acting anaesthetic, bupivacaine, inferior tetracaine. Limited supervised use anaesthetics is recommended controlling following photorefractive keratectomy.