Trichostatin A Inhibits Corneal Haze in vitro and in vivo
作者： Ajay Sharma , Maneesh M. Mehan , Sunilima Sinha , John W. Cowden , Rajiv R. Mohan
DOI: 10.1167/IOVS.08-2919
关键词:
摘要: PURPOSE Trichostatin A (TSA), a histone deacetylase inhibitor, has been shown to suppress TGF-β-induced fibrogenesis in many nonocular tissues. The authors evaluated TSA cytotoxicity and its antifibrogenic activity on TGF-β– driven fibrosis the cornea with use of vitro vivo models.
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