Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension.
作者： B. H. Jiang , G. L. Semenza , C. Bauer , H. H. Marti
DOI: 10.1152/AJPCELL.1996.271.4.C1172
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摘要: … genes encoding erythropoietin, glycolytic enzymes, and vascular endothelial growth factor in hypoxic mammalian cells. In this study, we have quantitated HIF-1 DNA-binding activity and …
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sci-hub.se 参考文章(32)
Gregg L. Semenza, Regulation of erythropoietin production. New insights into molecular mechanisms of oxygen homeostasis. Hematology-oncology Clinics of North America. ,vol. 8, pp. 863- 884 ,(1994) , 10.1016/S0889-8588(18)30134-5
C. W. Pugh, C. C. Tan, R. W. Jones, P. J. Ratcliffe, Functional analysis of an oxygen-regulated transcriptional enhancer lying 3' to the mouse erythropoietin gene. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 88, pp. 10553- 10557 ,(1991) , 10.1073/PNAS.88.23.10553
E. Hoffman, H Reyes, F. Chu, F Sander, L. Conley, B. Brooks, O Hankinson, Cloning of a factor required for activity of the Ah (dioxin) receptor Science. ,vol. 252, pp. 954- 958 ,(1991) , 10.1126/SCIENCE.1852076
H. Reyes, S. Reisz-Porszasz, O. Hankinson, Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor. Science. ,vol. 256, pp. 1193- 1195 ,(1992) , 10.1126/SCIENCE.256.5060.1193
FRANKLIN H. EPSTEIN, YORAM AGMON, MAYER BREZIS, Physiology of Renal Hypoxiaa Annals of the New York Academy of Sciences. ,vol. 718, pp. 72- 82 ,(2008) , 10.1111/J.1749-6632.1994.TB55706.X
Yuxiang Liu, Shanna R. Cox, Toshisuke Morita, Stella Kourembanas, Hypoxia Regulates Vascular Endothelial Growth Factor Gene Expression in Endothelial Cells Identification of a 5′ Enhancer Circulation Research. ,vol. 77, pp. 638- 643 ,(1995) , 10.1161/01.RES.77.3.638
M. Goldberg, S. Dunning, H. Bunn, Regulation of the erythropoietin gene: evidence that the oxygen sensor is a heme protein Science. ,vol. 242, pp. 1412- 1415 ,(1988) , 10.1126/SCIENCE.2849206
Eugene D. Robin, Brian J. Murphy, James Theodore, Coordinate regulation of glycolysis by hypoxia in mammalian cells. Journal of Cellular Physiology. ,vol. 118, pp. 287- 290 ,(1984) , 10.1002/JCP.1041180311
F C White, S M Carroll, A Magnet, C M Bloor, Coronary collateral development in swine after coronary artery occlusion. Circulation Research. ,vol. 71, pp. 1490- 1500 ,(1992) , 10.1161/01.RES.71.6.1490
Marie A. Gilles-Gonzalez, Gary S. Ditta, Donald R. Helinski, A HAEMOPROTEIN WITH KINASE ACTIVITY ENCODED BY THE OXYGEN SENSOR OF RHIZOBIUM MELILOTI Nature. ,vol. 350, pp. 170- 172 ,(1991) , 10.1038/350170A0