Exogenous Melatonin: Its Relationship to Prolactin and Its Efficacy at Reducing or Alleviating Stress.

摘要: Abstract : Recently we completed a study designed to investigate the effect of melatonin administration (10 mg) at 1300 on menstrual characteristics, prolactin, and premenstrual syndrome-like symptoms during simulated eastward deployment. Bright lights were utilized simulate movement across six time zones. During analysis biochemical results, made fortuitous discovery that appears alleviate stress associated with in-house The was double blind placebo controlled. Melatonin given healthy females for 5 consecutive days late follicular early luteal phases cycle. Volunteers spent 24 hours in hospital before entering dose phase again last day. On those 2 days, hourly blood samples collected from an in-dwelling catheter used prolactin. also profile moods state questionnaire upon waking each 8 which overlapped days. group showed prolactin peak day/blood draw, while 1500. It is well known stimulates release 2-hour delay between within normal expected delay.