Importance of Surgical Resection in the Successful Management of Soft Tissue Sarcoma

摘要: Hypothesis A systemic disease-free state necessitates a local state. This cannot be accomplished without properly performed resection by an experienced surgical team. Successful management of soft tissue sarcoma (STS) may lead to improved survival. An STS treatment protocol using wide excision followed radiation therapy is effective in achieving tumor control and survival similar that multiple-modality regimens, but with lower morbidity. Design Retrospective cohort review (August 1, 1987, May 6, 1998). Setting Referral single musculoskeletal oncologic surgeon, surgery at tertiary care medical center large urban area. Patients Ninety patients the trunk or extremities. Interventions Preoperative evaluation included surveillance computed tomographic scan chest, magnetic resonance imaging primary site assess extent plan approach, angiography if vascular bypass was proposed. Wide performed, concomitant and/or complex plastic reconstruction as needed. Postoperative given most patients. Adjuvant chemotherapy used selectively. Main Outcome Measures Morbidity, recurrence rates, Results Histologically negative margins were obtained 89 (99%) 90 patients; 86 (96%) remained free disease follow-up. Five died metastatic disease. Conclusion Excellent aggressive, appropriate only selective high-risk leads excellent survival, low morbidity good functional outcome.