Analytical Review: Hemostatic Homeostasis

摘要: Preservation of the blood fluidity is a primary prerequisite for maintenance circulation and consequently life itself. The protection against loss this accordingly most effective. Since coagulation sequential process involving successive activation multiple proenzymes79,80 since each activated enzyme subject to neutralization in plasma cellular clearance, it must be extremely difficult achieve significant degree later clotting factors circulating blood. This interpretation hemostatic homeostasis provides theoretical basis doubting as continuous generalized vivo; buttresses experimental evidence hypothesis.81 Seen from different perspective, above concept teleological reason complexity process: so many steps are required, great variety independent mechanisms available controlling them, there corresponding safety having control unavailable total destruction by single disrupting pathway.