In vitro investigation of electrophoretically deposited bioactive hydroxyapatite/chitosan coatings reinforced by graphene
作者： Marija Đošić , Sanja Eraković , Ana Janković , Maja Vukašinović-Sekulić , Ivana Z. Matić
DOI: 10.1016/J.JIEC.2016.12.004
关键词:
摘要: Abstract Graphene (Gr) and natural polymer chitosan (CS) were introduced to hydroxyapatite (HAP) produce a three-component composite coating, which was fabricated by cathodic electrophoretic deposition on Ti substrates in an ethanol suspension. These HAP/CS/Gr coatings characterized X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), thermogravimetric analysis (TGA), photoelectron (XPS) electrochemical measurements found that the graphene into HAP/CS composites significantly improves their morphology, thermal stability, bioactivity. Both are classified as non-cytotoxic when tested against healthy peripheral blood mononuclear cells (PBMC), while antibacterial activity Staphylococcus aureus Escherichia coli could not be verified.
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