Seronegative reactive spondyloarthritis and the skin.

摘要: Spondyloarthritidies represent a group of conditions affecting the axial and peripheral muscoloskeletal apparatus are often associated with psoriasis, infections, inflammatory bowel diseases. Other diseases included in this category psoriatic arthritis, ankylosing spondylitis, enteropathic arthritis. Reactive arthritis is an elusive spondyloarthritis, commonly occurring 1 to 3 weeks after digestive or genitourinary tract infection, which microorganisms do not infect joint directly. classically characterized by large-joint urethritis men cervicitis women, eye inflammation (usually conjunctivitis uveitis) but encompasses numerous other symptoms signs, including manifestations dermatologic interest such as keratoderma blenorrhagicum circinate balanitis. The diagnosis reactive clinical, infectious agent cannot always be identified due disease latency infection. Most cases self-limiting, may become chronic 30% cases. Treatment options include anti-inflammatory drugs, steroids, sulfasalazine; biologic agents, tumor necrosis factor α (TNF-α) blockers, have been recently used, there only few randomized clinical trials on treatment effectiveness antimicrobials needs further evaluation.