5.10 Interactions of Antimicrobial Peptides with Lipid Bilayers

作者: P.F. Almeida , A. Pokorny

DOI: 10.1016/B978-0-12-374920-8.00515-4

关键词:

摘要: The interactions of antimicrobial peptides with model lipid bilayer membranes are discussed. topics covered include the structures peptides, which usually amphipathic; thermodynamics binding to membrane surface, contributions from hydrophobic effect, secondary structure formation, and electrostatic interactions; kinetics peptide induced leakage vesicles; molecular models proposed describe perturbation or pore formation; nature pores, may be transient disordered; role lipids in as described by dynamics elastic properties.

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