Multilocus and Multitrait Measures of Differentiation for Gene Markers and Phenotypic Traits

作者: Antoine Kremer , Anne Zanetto , Alexis Ducousso

DOI: 10.1093/GENETICS/145.4.1229

关键词:

摘要: Multilocus measures of differentiation taking into account gametic disequilibrium are developed. Even if coupling and repulsion heterozygotes cannot be separated at the multilocus level, a method is given to calculate composite measure (CF(st)) zygotic which accounts for allelic associations combining both nongametic effects. Mean maximum differentiations may relevant when computed. Maximum highest eigenvalue F(st) matrix, whereas mean corresponds value all eigenvalues matrix. Gametic has stronger effect on than takes anisotropy that exist between within- between-population components disequilibria. calculated set 81 Quercus petraea (sessile oak) populations assessed with eight allozyme loci two phenotypic traits (bud burst height growth). The results indicate increases as more (traits) considered remains constant or decreases. Phenotypic exhibit higher population allozymes. applications uses further discussed.

参考文章(34)
S. S. WILKS, CERTAIN GENERALIZATIONS IN THE ANALYSIS OF VARIANCE Biometrika. ,vol. 24, pp. 471- 494 ,(1932) , 10.1093/BIOMET/24.3-4.471
S. N. Roy, On a Heuristic Method of Test Construction and its use in Multivariate Analysis Annals of Mathematical Statistics. ,vol. 24, pp. 220- 238 ,(1953) , 10.1214/AOMS/1177729029
Tomoko Ohta, Motoo Kimura, Linkage disequilibrium due to random genetic drift Genetics Research. ,vol. 13, pp. 47- 55 ,(1969) , 10.1017/S001667230000272X
T. Ohta, Linkage disequilibrium due to random genetic drift in finite subdivided populations. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 79, pp. 1940- 1944 ,(1982) , 10.1073/PNAS.79.6.1940
K. C. S. Pillai, Some New Test Criteria in Multivariate Analysis Annals of Mathematical Statistics. ,vol. 26, pp. 117- 121 ,(1955) , 10.1214/AOMS/1177728599
Tomoko Ohta, Linkage disequilibrium with the island model. Genetics. ,vol. 101, pp. 139- 155 ,(1982) , 10.1093/GENETICS/101.1.139