Predictive Factors for Death After Snake Envenomation in Myanmar

作者: Kyi-Phyu Aye , Vipa Thanachartwet , Chit Soe , Varunee Desakorn , Supat Chamnanchanunt

DOI: 10.1016/J.WEM.2018.01.001

关键词:

摘要: Introduction Factors predictive for death from snake envenomation vary between studies, possibly due to variation in host genetic factors and venom composition. This study aimed evaluate Myanmar. Methods A prospective was performed among adult patients with snakebite admitted tertiary hospitals Yangon, Myanmar, May 2015 August 2016. Data including clinical variables laboratory parameters, management, outcomes were evaluated. Multivariate regression analysis at the time of presentation hospital. Results Of 246 recruited into study, 225 (92%) survived 21 (8%) died during hospitalization. The species responsible a bite identified 74 (30%) patients; majority bites Russell's vipers (63 patients, 85%). independent included 1) duration arrival hospital >1 h (odds ratio [OR]: 9.0, 95% confidence interval [CI]: 1.1–75.2; P =0.04); 2) white blood cell counts >20 ×10 3 cells·μL -1 (OR: 8.9, CI: 2.3–33.7; =0.001); 3) presence capillary leakage 3.7, 1.2–11.2; =0.02). delay antivenom administration >4 increases risk (11/21 deaths). Conclusions Patients who present these should be recognized provided early appropriate intervention reduce mortality rate adults

参考文章(24)
Esaú L Feitosa, Vanderson S Sampaio, Jorge L Salinas, Amanda M Queiroz, Iran Mendonça da Silva, André A Gomes, Jacqueline Sachett, André M Siqueira, Luiz Carlos L Ferreira, Maria Cristina Dos Santos, Marcus Lacerda, Wuelton Monteiro, None, Older Age and Time to Medical Assistance Are Associated with Severity and Mortality of Snakebites in the Brazilian Amazon: A Case-Control Study PLOS ONE. ,vol. 10, pp. e0132237- ,(2015) , 10.1371/JOURNAL.PONE.0132237
Jaideep C. Menon, Joseph K. Joseph, Complications of Hemotoxic Snakebite in India ,(2015)
Shraddha M Pore, Sunita J Ramanand, Praveenkumar T Patil, Alka D Gore, Mayur P Pawar, Smita L Gaidhankar, Ravi R Ghanghas, None, A retrospective study of use of polyvalent anti-snake venom and risk factors for mortality from snake bite in a tertiary care setting. Indian Journal of Pharmacology. ,vol. 47, pp. 270- 274 ,(2015) , 10.4103/0253-7613.157117
Bilal Elbey, Burhan Baykal, Ümit Can Yazgan, Yılmaz Zengin, The prognostic value of the neutrophil/lymphocyte ratio in patients with snake bites for clinical outcomes and complications Saudi Journal of Biological Sciences. ,vol. 24, pp. 362- 366 ,(2017) , 10.1016/J.SJBS.2015.10.002
TusharB Patil, MadhuriM Paithankar, MangeshB Patil, TejendraS Chaudhari, RaginiV Gulhane, Predictors of mortality in patients of poisonous snake bite: Experience from a tertiary care hospital in Central India International journal of critical illness and injury science. ,vol. 4, pp. 101- 107 ,(2014) , 10.4103/2229-5151.134145
N Suchithra, J M Pappachan, P Sujathan, Snakebite envenoming in Kerala, South India: clinical profile and factors involved in adverse outcomes. Emergency Medicine Journal. ,vol. 25, pp. 200- 204 ,(2008) , 10.1136/EMJ.2007.051136
Suresh David, Sarah Matathia, Solomon Christopher, Mortality Predictors of Snake Bite Envenomation in Southern India—A Ten-Year Retrospective Audit of 533 Patients Journal of Medical Toxicology. ,vol. 8, pp. 118- 123 ,(2012) , 10.1007/S13181-011-0204-0
Shigehiko Karino, Bradley J. Willcox, Kaon Fong, Serena Lo, Robert Abbott, Kamal H. Masaki, Total and differential white blood cell counts predict eight-year incident coronary heart disease in elderly Japanese-American men: The Honolulu Heart Program Atherosclerosis. ,vol. 238, pp. 153- 158 ,(2015) , 10.1016/J.ATHEROSCLEROSIS.2014.12.003
A.G. Habib, S.B. Abubakar, Factors affecting snakebite mortality in north-eastern Nigeria International Health. ,vol. 3, pp. 50- 55 ,(2011) , 10.1016/J.INHE.2010.08.001
M Levi, CH Toh, J Thachil, HG Watson, None, Guidelines for the diagnosis and management of disseminated intravascular coagulation British Journal of Haematology. ,vol. 145, pp. 24- 33 ,(2009) , 10.1111/J.1365-2141.2009.07600.X