Diagnosis and management of interstitial pregnancy - a series of eleven cases

摘要: aDepartement de gynecologie, obstetrique et genetique, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland b Departement gynecologie obstetrique, Hopital du Chablais, Aigle, Summary PRINCIPLES: Interstitial pregnancy represents 2% of ectopic pregnancies, but it is a highly morbid condition with 2.5% maternal mortality. Its diagnostic and therapeutic management remains controversial. The aim this review to describe the interstitial in our institution between 2001 2011 define some general rules for clinical practice. METHODS: Single retrospective study. RESULTS: Eleven women were treated pregnancy. median age was 33 years gestity 4. Seven patients had history gynaecological surgery four pregnancies followed vitro fertilisation. diagnosis made at gestational seven weeks beta-HCG level 5,838 U/l. Six eleven received an initial treatment intracornual methotrexate, three intramuscular methotrexate two surgery. time resolution 58 days. Three needed second line treatment: after one methotrexate. further delivered by caesarean section. CONCLUSIONS: A high prevalence previous resulting from fertilisation observed. earliness factor that allowed conservative most cases. Beta-HCG follow up fundamental allowing therapy can persist over long period must be taken into account due its possible psychological impact. Intracornual seems more efficacious than series.