Three-dimensional structure of bactericidal/permeability-increasing protein (BPI)
作者： Lesa J. Beamer , David Eisenberg , Stephen F. Carroll
DOI:
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摘要: The present invention provides a crystallized Bactericidal Permeability-Increasing (BPI) protein; methods for x-ray diffraction analysis to provide patterns of sufficiently high resolution three-dimensional structure determination the protein, as well rational drug design, based on using amino acid sequence data and/or crystallography provided computer readable media, analyzed system having suitable algorithms; and atomic coordinates are yielding structural information lipid binding transport protein family that includes BPI, LBP, CETP PLTP.
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