Surface Cell Growth Engineering Assisted by a Novel Bacterial Nanomaterial

摘要: The polypeptide chains that form IBsusually retain a certain amount of native structure, keepingtheir biological activity (e.g., fluorescence or enzymatic activity),and as result being suitable for use functional andbiocompatible materials. In this study we characterize therelevant nanometer-scale properties IBs and explore the extentto which they can be tailored by simple approaches. addition,as an intriguing proof-of-concept, IB-grafted surfaces have beenobtained dramatically stimulate mammalian cell prolifera-tion, proving potential in tissue engineering andregenerative medicine.Many recombinant polypeptides produced bacteria aggre-gate IBs. These protein deposits appear highly hydrated,chemically pure particles, itself is themain component — up to around 95% therein.