Papel del tejido perivascular en la regulación del tono vascular: repercusión en el uso de puentes aorto-coronarios para revascularización miocárdica

摘要: Since more than thirty years, surgical insertion of autologous aortocoronary bypasses from saphenous vein and mammary artery constitute the election treatment for patients with severe coronary disease. The lifespan these grafts has shown to be longer arterial tissue even though its use is limited by restricted availability. This why bypasses, although having a greater risk presenting occlusion, are most used in procedures myocardial reperfusion. reasons which venous occluded after site still not clear; nevertheless, it been proposed that could due different factors such as: mechanical trauma, increment pressure diminished friction stress. In 1996 «no-touch» preparation technique was described, were implanted along surrounding perivascular demonstrated improve this type grafts. Recently fat play role vascular tone regulation described existence an adipose cell derived relaxing factor (ADRF), whose nature completely cleared yet. objective article review related grafts’ possible physiopathologic channels form phenomenon, new alternatives advances description ADRF regulation.