The protective effect of caffeic acid phenethyl ester (CAPE) on oxidative stress in rat liver exposed to the 900 MHz electromagnetic field.

摘要: In this study, we aimed to investigate the possible protective effects of caffeic acid phenethyl ester (CAPE) on lipid peroxidation (LPO) and activities antioxidant enzymes in liver rats exposed 900 MHz electromagnetic field (EMF). EMF cellular phones may affect biological systems by increasing free radical, which appear mainly enhance LPO, changing antioxidative liver, thus leading oxidative damage. CAPE, an active component propolis extract, exhibits properties several studies suggest that supplementation with can influence exposure induced hepatotoxicity. Thirty male Sprague-Dawley were divided into three groups: control (n = 10), 10) + CAPE 10). was injected intraperitoneally for 30 days before EMF. Liver tissue removed study catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), xanthine oxidase (XO) levels LPO. The XO, CAT level LPO increased (EMF) group compared group, although decreased administration. SOD GSH-Px their It be concluded prevent EMF-induced changes strengthening defense system reducing reactive oxygen species enzyme activities.