Pitfalls in MR measurement of tissue blood flow with intravascular tracers: Which mean transit time?

摘要: Measuring tissue blood flow with NMR imaging of intravascular tracers is more difficult than measurements volume. One major obstacle to the application Central Volume Principle direct measurement mean transit time. In this note, we demonstrate that time (MTT), which relates volume via Principle, not first moment concentration-time curve for MR or CT purely tracers. However, while methods cannot be used by themselves determine absolute flow, show curves may provide a useful relative measure example, considering ratios moments.