Hepatic cirrhosis and hepatitis: MR imaging enhanced with superparamagnetic iron oxide.

摘要: Superparamagnetic iron oxide was applied as a reticuloendothelial contrast agent in the diagnosis of cirrhosis and hepatitis seven patients. Three patients had compensated cirrhosis, four active hepatitis. T1- T2-weighted spin-echo magnetic resonance images were obtained before 1 hour after administration oxide. Eight without diffuse liver disease served control group. Normal tissue showed 75% +/- 9% reduction signal intensity oxide, appeared homogeneously hypointense. Cirrhotic smaller response (P less than .05) to with 52% 13% intensity. Inhomogeneous structures could be observed enhanced are thought represent fibrous bands or regenerating nodules. Liver markedly reduced (11% 2%) .05), parenchyma homogeneous. The authors conclu...