Encapsulation of Insulin Producing Cells for Diabetes Treatment Using Alginate and Cellulose Sulphate as Bioencapsulation Polymers

摘要: It has long been the holy grail of cell encapsulation to treat diabetes with insulin producing cells that are shielded from rejection or clearance by host immune system. Indeed, idea around for more than 50 years first demonstration in an animal model being published 1980 and patient treated reported 1994. In meantime, clinical experience accrued use encapsulated treatment human diabetes. Most these studies have focused on alginate as material although some promising data obtained is reviewed this article, it still far a product can be routinely applied. Cellulose sulphate excellent properties making ideal shown safe 27 patients. Moreover, showing safety efficacy rat supporting cellulose might choice application. DOI:10.14437/2377-7206-1-102 Review Brian Salmons,