Influence of bromocriptine on free amino acids in the kidneys and heart of the rat
作者： Abdulrahman M. Ageel , Kamal E.H.El Tahir , Abdulrahim Abu-Jayyab
DOI: 10.1016/0006-2952(87)90673-3
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摘要: Abstract The effects of bromocriptine, sulpiride or their combination on free amino acids in the kidneys and heart after acute chronic treatment rats were investigated, using an automatic LKB Amino Acid Analyzer. Bromocriptine at a single dose 4 10 mg/kg (i.p.) did not affect level any acid; however, 20 it significantly elevated content taurine kidney from 7.00 ± 0.30 to 9.70 0.1 22.9 1.7 30 1.2 μ mol/g wet tissue (P N = 7). It also increased glutamic acid 3 4.5 0.25 −1 · day ) for 5 weeks 7.2 0.3 (control) 11.1 0.90 23.1 38.8 1.8 tissue. cardiac 4.8 0.24 2 receptors by bromocriptine. Due similarities between bromocriptine affected renal actions, is suggested that mobilization may least part contribute towards bromocriptine-induced actions.
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sci-hub.se 参考文章(15)
F. Franconi, A. Giotti, S. Manzini, F. Martini, I. Stendardi, L. Zilletti, Observations on the Action of Taurine at Arterial and Cardiac Levels Advances in Experimental Medicine and Biology. ,vol. 139, pp. 181- 190 ,(1982) , 10.1007/978-1-4757-0402-0_12
R.N. Willette, P.P. Barcas, A.J. Krieger, H.N. Sapru, Vasopressor and depressor areas in the rat medulla. Identification by microinjection of L-glutamate. Neuropharmacology. ,vol. 22, pp. 1071- 1079 ,(1983) , 10.1016/0028-3908(83)90027-8
Amin T. Hamed, James Z. Ginos, Robert D. Ekas, Bhagavan S. Jandhyala, Mustafa F. Lokhandwala, Renal hemodynamics in hemorrhagic hypotension: studies on the effects of pre- and postjunctional dopamine receptor agonists. Journal of Cardiovascular Pharmacology. ,vol. 5, pp. 207- 212 ,(1983) , 10.1097/00005344-198303000-00007
R. H FALK, R. D DESILVA, B. LOWN, Reduction in vulnerability to ventricular fibrillation by bromocriptine, a dopamine agonist Cardiovascular Research. ,vol. 15, pp. 175- 180 ,(1981) , 10.1093/CVR/15.3.175
Karen E. Lee, R. A. Summerill, GLOMERULAR FILTRATION RATE FOLLOWING ADMINISTRATION OF INDIVIDUAL AMINO ACIDS IN CONSCIOUS DOGS Quarterly Journal of Experimental Physiology. ,vol. 67, pp. 459- 465 ,(1982) , 10.1113/EXPPHYSIOL.1982.SP002661
Hideji Morishita, Michiyo Sugiyama, Tatsuo Furukawa, Inhibition by sulfur-containing amino acids and GABA of sympathetic neurotransmission in guinea-pig vas deferens. European Journal of Pharmacology. ,vol. 95, pp. 13- 19 ,(1983) , 10.1016/0014-2999(83)90262-5
John W. Kebabian, Donald B. Calne, Multiple receptors for dopamine. Nature. ,vol. 277, pp. 93- 96 ,(1979) , 10.1038/277093A0
Bengt Persson, Cardiovascular effects of intracerebroventricular GABA, glycine and muscimol in the rat Naunyn-schmiedebergs Archives of Pharmacology. ,vol. 313, pp. 225- 236 ,(1980) , 10.1007/BF00505738
A. Meister, On the Enzymology of Amino Acid Transport Science. ,vol. 180, pp. 33- 39 ,(1973) , 10.1126/SCIENCE.180.4081.33
Larry R. Bush, Susan Warren, Charles L. Mesh, Benedict R. Lucchesi, Comparative effects of aspartate and glutamate during myocardial ischemia. Pharmacology. ,vol. 23, pp. 297- 304 ,(1981) , 10.1159/000137565