Compounds and uses thereof for the modulation of hemoglobin

作者: Zhe Li , Qing Xu , Brian W. Metcalf , II Gwaltney , Stephen L.

DOI:

关键词:

摘要: Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods intermediates for their preparation, use in treating disorders mediated by hemoglobin that would benefit from tissue and/or cellular oxygenation.

参考文章(495)
Valentino Stella, Ronald Borchardt, Michael Hageman, Reza Oliyai, Hans Maag, Jefferson Tilley, None, Prodrugs : challenges and rewards Springer , AAPS Press. ,(2007)
Keith Stuart Klemba, Marta Maria Kosarchyn, Norman Kincl, Method for storing relationships in object-oriented computing systems ,(1992)
Steven Deem, Red Blood Cells and Hemoglobin in Hypoxic Pulmonary Vasoconstriction Advances in Experimental Medicine and Biology. ,vol. 588, pp. 217- 231 ,(2006) , 10.1007/978-0-387-34817-9_19
Anthony M. Lear, Anthony P. Rawlinson, Peter J. Price, Carbonylation of methanol ,(1991)
Bernard Loev, James R. Shroff, Dihydropyridines and their use in the treatment of asthma ,(1983)
Takayuki Shioda, Sadayuki Arimori, Tetrazolinone compound and use thereof ,(2014)
Catherine Howsham, Ian Bruce, Lee Edwards, Emma Budd, Pyridines and pyrazines as inhibitors of pi3k ,(2009)
Jian-Xin Duan, Mark Matteucci, Hypoxia-Activated Anti-Cancer Agents ,(2005)
Frans A. Kuypers, Sandra Larkin, Marcel Fens, Susan Knox, William Fitch, Bryan T. Oronsky, Pedro Cabrales, Jan Scicinski, Chad Brouse, Methods and compositions comprising a nitrite-reductase promoter for treatment of medical disorders and preservation of blood products ,(2012)