Photopolymerized maleilated chitosan/thiol-terminated poly (vinyl alcohol) hydrogels as potential tissue engineering scaffolds

作者: Yingshan Zhou , Shuyan Zhao , Can Zhang , Kaili Liang , Jun Li

DOI: 10.1016/J.CARBPOL.2018.01.009

关键词:

摘要: Abstract Photocrosslinkable hydrogels composed of natural materials exhibit great application potential in tissue engineering scaffolds. However, weak formation and poor mechanical property can usually be a limitation. Herein, the photo-clickable thiol-ene based chitosan were synthesized using photopolymerization maleic (MCS) thiol-terminated poly (vinyl alcohol) (TPVA) presence biocompatible photoinitiator. Rheological absorbing behavior MCS/TPVA could tailored by varying amount TPVA feed. There was strong intermolecular hydrogen bonding between molecules MCS TPVA. Notably, hydrogel (MT-3) exhibited rapid gelation (

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