Human SSAV-related endogenous retroviral element: LTR-like sequence and chromosomal localization to 18q21

作者: Ruth Brack-Werner , David E. Barton , Thomas Werner , Brigitte E. Foellmer , Christine Leib-Mösch

DOI: 10.1016/0888-7543(89)90316-9

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摘要: A new family of human endogenous retroviral sequences was recently discovered by way its relationship to the simian sarcoma-associated virus (SSAV). One molecular clone, termed S71, contains related genes coding for group-specific antigens (gag) and polymerase (pol) proteins SSAV. At 3' end this element we have now found a 535-bp region which shows features characteristics long terminal repeat, including potential signal essential transcriptional control. By means Southern blotting in situ hybridization, sequence mapped chromosome 18 band q21.

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