Oncolytic viruses for treatment of malignant brain tumours
作者： N. G. Rainov , H. Ren
DOI: 10.1007/978-3-7091-6090-9_17
关键词:
摘要: Wild type viruses have been known for decades their capability to destroy malignant tumour cells upon infection and intracellular replication. Genetic engineering of such was, however, only recently done in an attempt improve utility as biological anticancer agents. or recombinant able selectively while sparing normal tissue are oncolytic viruses. Most currently investigated clinical trials derived from adenovirus (AV) herpes simplex virus 1 (HSV1).
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Stefan J. Ries, Christian H. Brandts, Alicia S. Chung, Carola H. Biederer, Byron C. Hann, Ettie M. Lipner, Frank McCormick, W. Michael Korn, Loss of p14ARF in tumor cells facilitates replication of the adenovirus mutant dl1520 (ONYX-015) Nature Medicine. ,vol. 6, pp. 1128- 1133 ,(2000) , 10.1038/80466
Carla Heise, Terry Hermiston, Leisa Johnson, Gabriel Brooks, Adam Sampson-Johannes, Angelica Williams, Lyndah Hawkins, David Kirn, An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy Nature Medicine. ,vol. 6, pp. 1134- 1139 ,(2000) , 10.1038/80474
Fadlo Khuri, James Arseneau, Ian Ganly, David Kirn, Britta Randlev, Larry Romel, Joseph Kuhn, Phillip Maples, Todd McCarty, Tony Reid, Sam Kaye, Stephen Landers, John Nemunaitis, Selective Replication and Oncolysis in p53 Mutant Tumors with ONYX-015, an E1B-55kD Gene-deleted Adenovirus, in Patients with Advanced Head and Neck Cancer: A Phase II Trial Cancer Research. ,vol. 60, pp. 6359- 6366 ,(2000)
Amitabha Deb, S. Jaharul Haque, Trine Mogensen, Robert H. Silverman, Bryan R. G. Williams, RNA-dependent protein kinase PKR is required for activation of NF-kappa B by IFN-gamma in a STAT1-independent pathway. Journal of Immunology. ,vol. 166, pp. 6170- 6180 ,(2001) , 10.4049/JIMMUNOL.166.10.6170
Murali Ramachandra, Amena Rahman, Aihua Zou, Mei Vaillancourt, John A. Howe, Douglas Antelman, Barry Sugarman, G. William Demers, Heidrun Engler, Duane Johnson, Paul Shabram, Re-engineering adenovirus regulatory pathways to enhance oncolytic specificity and efficacy Nature Biotechnology. ,vol. 19, pp. 1035- 1041 ,(2001) , 10.1038/NBT1101-1035
Faris Farassati, An-Dao Yang, Patrick W. K. Lee, Oncogenes in Ras signalling pathway dictate host-cell permissiveness to herpes simplex virus 1 Nature Cell Biology. ,vol. 3, pp. 745- 750 ,(2001) , 10.1038/35087061
Tracy Terry-Allison, Rebecca I. Montgomery, J. Charles Whitbeck, Ruliang Xu, Gary H. Cohen, Roselyn J. Eisenberg, Patricia G. Spear, HveA (Herpesvirus Entry Mediator A), a Coreceptor for Herpes Simplex Virus Entry, also Participates in Virus-Induced Cell Fusion Journal of Virology. ,vol. 72, pp. 5802- 5810 ,(1998) , 10.1128/JVI.72.7.5802-5810.1998
F. Besnard, M. Brenner, Y. Nakatani, R. Chao, H.J. Purohit, E. Freese, Multiple interacting sites regulate astrocyte-specific transcription of the human gene for glial fibrillary acidic protein. Journal of Biological Chemistry. ,vol. 266, pp. 18877- 18883 ,(1991) , 10.1016/S0021-9258(18)55145-0
Keiro Ikeda, Tomotsugu Ichikawa, Hiroaki Wakimoto, Jonathan S. Silver, Thomas S. Deisboeck, Dianne Finkelstein, Griffith R. Harsh, David N. Louis, Raymond T. Bartus, Fred H. Hochberg, E. Antonio Chiocca, Oncolytic virus therapy of multiple tumors in the brain requires suppression of innate and elicited antiviral responses Nature Medicine. ,vol. 5, pp. 881- 887 ,(1999) , 10.1038/11320
Nancy L. Lill, Steven R. Grossman, Doron Ginsberg, James DeCaprio, David M. Livingston, Binding and modulation of p53 by p300/CBP coactivators Nature. ,vol. 387, pp. 823- 827 ,(1997) , 10.1038/42981