Assay for Multiple Vitamin D Metabolites

作者: Phillip W. Lambert , Irene Y. Fu , David M. Kaetzel , Bruce W. Hollis

DOI: 10.1007/978-1-4612-5553-6_6

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摘要: During the past decade there have been major advances in our knowledge of vitamin D metabolism and its role both physiologic pathophysiologic situations calcium (Ca) homeostasis. Critical to these has development ligand-binding assays for a wide spectrum D3 metabolites. Separate reported D,1,2 25-OHD,3–11 24,25-(OH)2D,12–15 25,26-(OH)2D,16–18 1,25-(OH)2D.19–35 More recently, methodology evolved measurement two or more metabolites single, relatively small plasma serum sample.23,28,34–42

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