Stop flow lithography in perfluoropolyether (PFPE) microfluidic channels

摘要: Stop Flow Lithography (SFL) is a microfluidic-based particle synthesis method for creating anisotropic multifunctional particles with applications that range from MEMS to biomedical engineering. Polydimethylsiloxane (PDMS) has been typically used construct SFL devices as the material enables rapid prototyping of channels complex geometries, optical transparency, and oxygen permeability. However, PDMS not compatible most organic solvents which limit current materials can be synthesized SFL. Here, we demonstrate fluorinated elastomer, called perfluoropolyether (PFPE), an alternative permeable elastomer microfluidic flow channels. We fabricate PFPE soft lithography synthesize in via process – this first demonstration lubrication layers non-PDMS channel. benchmark performance by comparing them devices. both under same conditions found difference dimensions was less than micron. greatly expand precursor processed because are chemically resistant solvents, inaccessible class reagents PDMS-based due swelling.