Dorsomedial striatal activity tracks completion of behavioral sequences
作者： Janak Ph , Janak Ph , Ottenheimer Dj , Ottenheimer Dj , Vandaele Y
DOI: 10.1101/2021.04.01.437899
关键词:
摘要: Abstract For proper execution of goal-directed behaviors, individuals require both a general representation the goal and an ability to monitor their own progress toward that goal. Here, we examine how dorsomedial striatum (DMS), region pivotal for forming associations among stimuli, actions, outcomes, encodes action sequences self-monitoring behavior. We trained rats complete sequence at least 5 consecutive lever presses (without visiting reward port) obtain recorded activity individual cells in DMS while performed task. found pattern gradually changed during sequence, permitting accurate decoding from neural population level. Moreover, this sequence-related was blunted on trials where did not sufficient number presses. Overall, these data suggest link between behavioral monitoring ongoing
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