Biosynthesis and Processing of the Cytoadhesins, GPIIb/IIIa and Vitronectin Receptor
作者： A. Troesch , A. Duperray , R. Berthier , G. Marguerie
DOI: 10.1007/978-1-4613-9003-9_10
关键词:
摘要: Integrins are heterodimers comprised of non covalently associated α and β subunits (1, 2). This family has been divided into four groups adhesion receptors, according to their subunit. Each group is composed glycoproteins sharing the same subunit different subunits. includes VLA (3), leukocyte proteins LFA-1, Mac-1 p 150,95 (4), cytoadhesin (5), newly identified epithelial integrin (6). The platelet GPIIb/IIIa vitronectin receptor (VNR) belong (5) share subunit, i.e. GPIIIa or VNRβ (7), its primary sequence (8–10) distinct a subunits, GPIIb VNRα (11–13).
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