Transport of mRNA through the nuclear pore in Plasmodium falciparum

摘要: The nucleus is the most important part of cell and vital for eukaryotic survival. It stores necessary geneticinformation separates protects this from rest cellular components. nuclear envelope that surroundsthe a double membrane with multiple pores composed an outer inner phospholipid bilayer.The communicates through pores, which are numerous tiny openings in nuclearenvelope, exchanges proteins RNA range processes. allow thepassage ATP, ions, water, other small molecules freely, but it regulates passage macromolecules. Thisphenomenon commonly known as nucleocytoplasmic transport (NCT) (Fahrenkrog Aebi 2003). Nuclear porecomplexes (NPCs) large macromolecular structures embedded envelope, control flowbetween cytoplasm. NPCs fuse both to make aqueous translocationchannels NCT into out (Raices D'Angelo 2012).NPCs highly selective, bidirectional transporter variety cargoes. copies ofnearly 30 different proteins, nucleoporins or Nups form largest multiprotein assemblies thecell (Alber et al. 2007).