Physiologically relevant increase in temperature causes an increase in intestinal epithelial tight junction permeability.
作者： Karol Dokladny , Pope L. Moseley , Thomas Y. Ma
关键词:
摘要: The effects of physiologically relevant increase in temperature (37–41° C) on intestinal epithelial tight junction (TJ) barrier have not been previously studied. Additionally, the role of heat-shock proteins (HSPs) in the regulation of intestinal TJ barrier during heat stress remains unknown. Because heat-induced disturbance of intestinal TJ barrier could lead to endotoxemia and bacterial translocation during physiological thermal stress, the purpose of this study was to investigate the effects of modest, physiologically relevant increases in …
elsevier.com
sci-hub.se 参考文章(78)
K. C. Kregel, P. T. Wall, C. V. Gisolfi, Peripheral vascular responses to hyperthermia in the rat. Journal of Applied Physiology. ,vol. 64, pp. 2582- 2588 ,(1988) , 10.1152/JAPPL.1988.64.6.2582
Gaffin Sl, Brock-Utne Jg, Wells Mt, Gathiram P, Antilipopolysaccharide improves survival in primates subjected to heat stroke Circulatory shock. ,vol. 23, pp. 157- 164 ,(1987)
Gaffin Sl, Brock-Utne Jg, Wells Mt, Gathiram P, Raidoo D, Portal and systemic plasma lipopolysaccharide concentrations in heat-stressed primates. Circulatory shock. ,vol. 25, pp. 223- 230 ,(1988)
S L Gaffin, J G Brock-Utne, M T Wells, P Gathiram, Time course of endotoxemia and cardiovascular changes in heat-stressed primates. Aviation, Space, and Environmental Medicine. ,vol. 58, pp. 1071- 1074 ,(1987)
Deitch Ea, Specian Rd, Baker J, Grisham Mb, Granger Dn, Ma Jw, Berg R, Ma L, Bridges W, Hemorrhagic shock-induced bacterial translocation is reduced by xanthine oxidase inhibition or inactivation. Surgery. ,vol. 104, pp. 191- 198 ,(1988)
Maddalena Donzelli, Claudia Negri, Angelo Mandarino, Laura Rossi, Ennio Prosperi, Isabelle Frouin, Rosa Bernardi, Alexander Burkle, A Ivana Scovassi, POLY(ADP-RIBOSE) SYNTHESIS : A USEFUL PARAMETER FOR IDENTIFYING APOPTOTIC CELLS Histochemical Journal. ,vol. 29, pp. 831- 837 ,(1997) , 10.1023/A:1026485622824
Gaffin Sl, Brock-Utne Jg, Wells Mt, Gathiram P, Prophylactic corticosteroid increases survival in experimental heat stroke in primates Aviation, Space, and Environmental Medicine. ,vol. 59, pp. 352- 355 ,(1988)
Alexander Bürkle, Hans A. Kretzschmar, David R. Brown, Poly(ADP-ribose) immunostaining to detect apoptosis induced by a neurotoxic fragment of prion protein. Histochemical Journal. ,vol. 31, pp. 711- 716 ,(1999) , 10.1023/A:1003944314206
R. C. Kukreja, M. C. Kontos, K. E. Loesser, S. K. Batra, Y. Z. Qian, C. J. Gbur, S. A. Naseem, R. L. Jesse, M. L. Hess, Oxidant stress increases heat shock protein 70 mRNA in isolated perfused rat heart. American Journal of Physiology-heart and Circulatory Physiology. ,vol. 267, ,(1994) , 10.1152/AJPHEART.1994.267.6.H2213
Paul R. Saunders, Javier Santos, Nico P.M. Hanssen, Derrick Yates, Jack A. Groot, Mary H. Perdue, Physical and psychological stress in rats enhances colonic epithelial permeability via peripheral CRH. Digestive Diseases and Sciences. ,vol. 47, pp. 208- 215 ,(2002) , 10.1023/A:1013204612762