Tyrosine kinase activity and transformation potency of bcr-abl oncogene products.

作者: T. Lugo , A. Pendergast , A. Muller , O. Witte

DOI: 10.1126/SCIENCE.2408149

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摘要: … Focus formation in soft agar by Rat 1 fibroblasts after acute … that cells were plated in soft agar 48 hours after infection. … hu,B-pol mRNA relative to Jurkat cells (15). However, this level is …

参考文章(14)
J B Konopka, R L Davis, S M Watanabe, A S Ponticelli, L Schiff-Maker, N Rosenberg, O N Witte, Only site-directed antibodies reactive with the highly conserved src-homologous region of the v-abl protein neutralize kinase activity. Journal of Virology. ,vol. 51, pp. 223- 232 ,(1984) , 10.1128/JVI.51.1.223-232.1984
J. Erikson, C. A. Griffin, A. ar-Rushdi, M. Valtieri, J. Hoxie, J. Finan, B. S. Emanuel, G. Rovera, P. C. Nowell, C. M. Croce, Heterogeneity of chromosome 22 breakpoint in Philadelphia-positive (Ph+) acute lymphocytic leukemia. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 83, pp. 1807- 1811 ,(1986) , 10.1073/PNAS.83.6.1807
S. Clark, J McLaughlin, M Timmons, A. Pendergast, Y Ben-Neriah, L. Dow, W Crist, G Rovera, S. Smith, O. Witte, Expression of a Distinctive BCR-ABL Oncogene in Ph1-positive Acute Lymphocytic Leukemia (ALL) Science. ,vol. 239, pp. 775- 777 ,(1988) , 10.1126/SCIENCE.3422516
J GROFFEN, J STEPHENSON, N HEISTERKAMP, A DEKLEIN, C BARTRAM, G GROSVELD, Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22 Cell. ,vol. 36, pp. 93- 99 ,(1984) , 10.1016/0092-8674(84)90077-1
André Hermans, Nora Heisterkamp, Marieke von Lindern, Sjozef van Baal, Dies Meijer, Dorien van der Plas, Leanne M. Wiedemann, John Groffen, Dirk Bootsma, Gerard Grosveld, Unique fusion of bcr and c-abl genes in Philadelphia chromosome positive acute lymphoblastic leukemia Cell. ,vol. 51, pp. 33- 40 ,(1987) , 10.1016/0092-8674(87)90007-9
S. Clark, J McLaughlin, W. Crist, R Champlin, O. Witte, Unique forms of the abl tyrosine kinase distinguish Ph1-positive CML from Ph1-positive ALL Science. ,vol. 235, pp. 85- 88 ,(1987) , 10.1126/SCIENCE.3541203
C. T. Denny, N. P. Shah, S. Ogden, C. Willman, T. McConnell, W. Crist, A. Carroll, O. N. Witte, Localization of preferential sites of rearrangement within the BCR gene in Philadelphia chromosome-positive acute lymphoblastic leukemia. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 86, pp. 4254- 4258 ,(1989) , 10.1073/PNAS.86.11.4254
Y Ben-Neriah, G. Daley, A. Mes-Masson, O. Witte, D Baltimore, The chronic myelogenous leukemia-specific P210 protein is the product of the bcr/abl hybrid gene. Science. ,vol. 233, pp. 212- 214 ,(1986) , 10.1126/SCIENCE.3460176
Annelies de Klein, Ad Geurts van Kessel, Gerard Grosveld, Claus R. Bartram, Anne Hagemeijer, Dirk Bootsma, Nigel K. Spurr, Nora Heisterkamp, John Groffen, John R. Stephenson, A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia Nature. ,vol. 300, pp. 765- 767 ,(1982) , 10.1038/300765A0
J. McLaughlin, E. Chianese, O. N. Witte, In vitro transformation of immature hematopoietic cells by the P210 BCR/ABL oncogene product of the Philadelphia chromosome Proceedings of the National Academy of Sciences of the United States of America. ,vol. 84, pp. 6558- 6562 ,(1987) , 10.1073/PNAS.84.18.6558