Noninvasive Cross-Sectional Observation of Three-Dimensional Cell Sheet-Tissue-Fabrication by Optical Coherence Tomography
作者： Yuji Haraguchi , Tatsuya Shimizu , Kiminori Mizuuchi , Hiroto Kawata , Mari Kobayashi
DOI: 10.1016/J.BBREP.2015.05.001
关键词:
摘要: Cell sheet engineering allows investigators/clinicians to prepare cell-dense three-dimensional (3-D) tissues, and various clinical trials with these fabricated tissues have already been performed for regenerating damaged tissues. sheets are easily manipulated 3-D can be rapidly by layering the cell sheets. This study used optical coherence tomography (OCT) noninvasively analyze following processes: (1) adhesions between layered sheets, (2) beating functional interaction of cardiac sheet-tissues fabricating thicker The tight couplings could observed cross-sectionally in real time. Importantly, noninvasive cross-sectional analyses OCT make possible fabricate confirming adherence technology would contribute regenerative medicine.
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