The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection
作者： Si Ming Man , Rajendra Karki , R K Subbarao Malireddi , Geoffrey Neale , Peter Vogel
DOI: 10.1038/NI.3118
关键词:
摘要: … type I interferon–dependent expression of IRF1, which drove the … Our results reveal a specific requirement for IRF1 and GBPs … under the control of IRF1, we infected wild-type and Irf1 −/− …
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