The Use of Antibodies in Diagnosis and Therapy of Cancer

作者: Asli Muvaffak , Nesrin Hasirci

DOI: 10.1007/978-1-4615-0063-6_23

关键词:

摘要: Immunology began as a study of the response living bodies to infections. Over years, it has become progressively more basic, passing through phases emphasis on serology, cellular immunology, molecular immunology and immunogenetics. also grown comprise many fields such immunochemistry, immunopathology, immunopharmacology, allergy, clinical tumor transplantation. It always provided an excellent mix fundamental applied sciences. The development monoclonal antibody (MoAb) technology by Kohler Milstein’ enormous opportunity for examination range issues, which previously seemed difficult handle. MoAbs were used in immunocytopathology, radioimmunoassays, enzyme-linked immunosorbent assays, flow cytometryin vitroandin vivofor diagnosis immunotherapy human disease.

参考文章(30)
David G. Maloney, Antonio J. Grillo-López, Christine A. White, David Bodkin, Russell J. Schilder, James A. Neidhart, Nalini Janakiraman, Kenneth A. Foon, Tina-Marie Liles, Brian K. Dallaire, Ken Wey, Ivor Royston, Thomas Davis, Ronald Levy, IDEC-C2B8 (Rituximab) Anti-CD20 Monoclonal Antibody Therapy in Patients With Relapsed Low-Grade Non-Hodgkin's Lymphoma Blood. ,vol. 90, pp. 2188- 2195 ,(1997) , 10.1182/BLOOD.V90.6.2188
Shiv Pillai, Abul K. Abbas, Andrew H. Lichtman, Cellular and Molecular Immunology ,(1994)
James H. Doroshow, Andrew A. Raubitschek, John E. Shively, Dave M. Yamauchi, Jeffrey Y. C. Wong, Sharon Wilczynski, Lawrence E. Williams, An Liu, Anna M. Wu, David Z. Chu, A phase I radioimmunotherapy trial evaluating 90yttrium-labeled anti-carcinoembryonic antigen (CEA) chimeric T84.66 in patients with metastatic CEA-producing malignancies. Clinical Cancer Research. ,vol. 6, pp. 3855- 3863 ,(2000)
Michael P. DiGiovanna, Elizabeth B. Claus, Tracey L. Davison, Peiguo Chu, David F. Stern, Christine L. Howe, Darryl Carter, Active Signaling by HER-2/neu in a Subpopulation of HER-2/neu-overexpressing Ductal Carcinoma in Situ Clinicopathological Correlates Cancer Research. ,vol. 62, pp. 6667- 6673 ,(2002)
Martin Brechbiel, Thomas A. Waldmann, Nicholas F. Landolfi, Kayhan Garmestani, Otto A. Gansow, Chuanchu Wu, Frank Hartmann, Eva Horak, Radioimmunotherapy targeting of HER2/neu oncoprotein on ovarian tumor using lead-212-DOTA-AE1. The Journal of Nuclear Medicine. ,vol. 38, pp. 1944- 1950 ,(1997)
Chen Wang, Dominick Amato, Rola Rabah, Jianing Zheng, Bernard Fernandes, Differentiation of monoclonal B lymphocytosis of undetermined significance (MLUS) and chronic lymphocytic leukemia (CLL) with weak CD5 expression from CD5− CLL Leukemia Research. ,vol. 26, pp. 1125- 1129 ,(2002) , 10.1016/S0145-2126(02)00062-0
Pierre Van Der Bruggen, Yi Zhang, Pascal Chaux, Vincent Stroobant, Christophe Panichelli, Erwin S Schultz, Jacques Chapiro, Benoît J Van den Eynde, Francis Brasseur, Thierry Boon, None, Tumor-specific shared antigenic peptides recognized by human T cells Immunological Reviews. ,vol. 188, pp. 51- 64 ,(2002) , 10.1034/J.1600-065X.2002.18806.X
T. Waldmann, Monoclonal antibodies in diagnosis and therapy. Science. ,vol. 252, pp. 1657- 1662 ,(1991) , 10.1126/SCIENCE.2047874
Lloyd J. Old, Immunotherapy for Cancer Scientific American. ,vol. 275, pp. 136- 143 ,(1996) , 10.1038/SCIENTIFICAMERICAN0996-136