Hemicrania continua: who responds to indomethacin?

摘要: Hemicrania continua (HC) is a primary headache disorder characterized by continuous, moderate to severe, unilateral and defined its absolute responsiveness indomethacin. However, some patients with the clinical phenotype of HC do not respond We reviewed records 192 putative diagnosis divided them into groups based on their headaches' response They were compared for age, gender, presence or absence specific autonomic symptoms, medication overuse, rapidity onset, whether headaches met criteria migraine when severe. Forty-three had an 122 did adequate doses The two differ significantly in terms sex, rapid-onset headache, overuse. Autonomic questionnaire, predict response. Eighteen could complete trial indomethacin due adverse events. Nine be included group despite improvement indomethacin: one patient probably cough another paroxysmal hemicrania; three improved but it was uncertain if they absolutely pain free, four dramatically still baseline headache. found no statistically significant differences between who All should receive Most suggestive