Macular Edema in Childhood Uveitis.

摘要: Background Pediatric uveitis is associated with a high incidence of severe and frequently permanent visual loss. This article summarizes the current understanding disease therapeutic options that are available to improve treatment outcomes. Methods A Medline search spanning last 10 years was undertaken using key terms “pediatric uveitis” or “childhood “macular edema”. Articles which appertained case reports small series were excluded from consideration, whereas those in opinions experts expressed, as well reviews, not. The information contained these latter two forms publication particularly valuable, owing scarcity prospective clinical data appertaining pediatric uveitis-associated macular edema. Results Ten ago, 34% children who presented manifested secondary complications at time diagnosis. During ensuing 3 treatment, this rose 86%. Heightening awareness earlier referrals expert centers, advent strategies involving anti-TNF agents intravitreal corticosteroids, have led decrease legal blindness affected eyes 18 – 69% below 8% during five-year course treatment. Conclusion Early diagnosis strict control inflammatory activity dramatic reduction vision-threatening complications. In majority cases, it has also been possible resolve cystoid edema, which, if insufficiently controlled by systemic therapy, usually responds dexamethasone implants.