Myeloproliferative Disorders and Myelodysplastic Syndromes

作者: Jo-Anne Vergilio , Adam Bagg

DOI: 10.1007/978-0-387-33227-7_35

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摘要: The myeloproliferative disorders (MPD) and myelodysplastic syndromes (MDS) encompass a pathologically clinically heterogeneous group of hematologic entities that are united by their putative origin from pluripotent hematopoietic stem cells. World Health Organization classifies these into three broad categories: (1) the chronic diseases, (2) syndromes, (3) myelodysplastic/myeloproliferative diseases1 (see Table 35-1). Though all true cell characteristically associated with bone marrow hyperplasia, they divergent in MPD typically effective hematopoiesis, while MDS ineffective reflected high or low peripheral blood counts, respectively.

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