作者: Nitza Goldenberg-Cohen , Miriam Ehrenberg , Helen Toledano , Liora Kornreich , Moshe Snir
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摘要: To characterize the severe postoperative irreversible visual loss induced by optic neuropathy in some children with a brain tumor, computerized database (2003-2008) of neuro-ophthalmology service major pediatric tertiary center was reviewed for all (counting fingers or less) due to brain-tumor-related at their last follow-up examination. Data on age, gender, etiology, initial symptoms and signs, acuity before after surgery exam, neuroimaging findings, treatment were collected. Of 240 children, 198 operated. those, 10 (5%, 5 boys girls) met study criteria. examination available 8 children: one had binocular blindness (uncertain light perception, counting fingers); 3 monocular already diagnosis (no fingers, no fixation); 6/60 vision worse eye; good bilaterally (6/10). Four direct nerve compression, 4 papilledema gliomas. (40%; craniopharyngioma, pineal germinoma, posterior fossa tumor) exhibited rapid deterioration tumor depression (1 compression increased intracranial pressure); two postoperatively; remained stable (after ≥5 visits), but did not improve. This shows that tumor-related may be associated marked inspite successful resection; 40% occurs perioeratively. Direct is main cause loss, while usually resolved without sequelae. However, autoregulatory changes responsible following decompression chronic papilledema. Clinicians need reminding about problem post-operative we speculate how it can avoided.