Macronutrients Intake and Incident Frailty in Older Adults: A Prospective Cohort Study

摘要: Background: Only a few studies have assessed the association between protein intake and frailty incidence obtained inconsistent results. This study examined of other macronutrient with risk in older adults. Methods: A prospective cohort 1,822 community-dwelling individuals aged 60 was recruited 2008-2010 followed-up through 2012. At baseline, food consumption validated, computerized face-to-face diet history. In 2012, were contacted again to ascertain incident frailty, defined as presence at least three five Fried criteria: low physical activity, slowness, unintentional weight loss, muscle weakness, exhaustion. Analyses performed using logistic regression adjusted for main confounders, including total energy intake. Results: During mean follow-up 3.5 years, 132 persons identified. The odds ratios (95% confidence interval) across increasing quartiles 1.00, 0.55 (0.32-0.93), 0.45 (0.26-0.78), 0.41 (0.23-0.72); p trend: .001. corresponding figures animal 0.68 (0.40-1.17), 0.56 (0.32-0.97), 0.48 (0.26-0.87), .011. And monounsaturated fatty acids (MUFAs), results 0.66 (0.37-1.20), 0.54 (0.28-1.02), 0.50 (0.26-0.96); .038. No found vegetable protein, saturated fats, long-chain ω-3 acids, α-linolenic acid, linoleic simple sugars, or polysaccharides frailty. Conclusion: Intake MUFAs inversely associated Promoting these nutrients might reduce